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KMID : 1134820150440101470
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Journal of the Korean Society of Food Science and Nutrition
2015 Volume.44 No. 10 p.1470 ~ p.1475
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Whitening Effect of Green Tea Seed Shell Ethanol Extracts
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Song Ha-Yeon
Sung Nak-Yun
Jung Pil-Mun
Kang Min-Soo
Park Won-Jeong
Byun Eui-Hong
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Abstract
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The objective of this study was to evaluate the whitening effect of green tea seed shell as an industrial byproduct. Green tea seed shell extract (GTSE) was obtained by ethanol extraction, and the yield was 1.24%. 1,1- Diphenyl-2-picrylhydrazyl radical scavenging and tyrosinase inhibitory activity of GTSE increased dose-dependently. To estimate inhibition of melanin synthesis, viability was tested in B16BL6 melanoma cells. GTSE treatment induced cytotoxicity at a concentration higher than 125 μg/mL but did not induce cytoxicity lower than 62.5 μg/mL. Thus, we fixed the optimal concentration at 62.5 μg/mL. Using this optimal concentration, melanin synthesis inhibition was measured, and GTSE treatment significantly reduced melanin synthesis induced by α-melanin stimulating hormone. Therefore, the results indicate that green tea seed shell extracts may have potential melanin synthesis inhibitory activity and may be useful for development of whitening material as a natural ingredient.
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KEYWORD
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green tea seed shell, anti-oxidant, tyrosinase, melanin synthesis, whitening activity
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